Best Commercial Space for Lease – Opportunities in Marylebone

Marylebone has long been regarded as one of the most desirable business districts in London. Combining elegant period architecture with modern commercial spaces, it offers businesses a prestigious address, excellent connectivity, and a vibrant mix of retail, dining, and cultural amenities.

For those looking for commercial space for lease, Marylebone provides a diverse range of options. From the historic charm of Baker Street to the creativity of Great Portland Street and the retail blend of Wigmore Street and James Street, each area within Marylebone has its own distinct appeal.

In this guide, we explore the best locations for commercial space for lease in Marylebone, highlighting key business hubs and what makes them ideal for different types of enterprises. Whether you are an established corporation, a boutique retailer, or a growing start-up, there is a perfect space waiting for you in this prime London district.

Baker Street – A hub of history and business

Baker Street is one of Marylebone’s most famous thoroughfares, best known for its association with Sherlock Holmes. However, beyond its literary fame, it has evolved into a thriving business hub, attracting a mix of corporate offices, financial services, and technology firms.

Why choose Baker Street for your business?

  • Prestigious location – Baker Street is synonymous with credibility and heritage, making it an appealing address for businesses that want to impress clients and investors.
  • Excellent transport links – Baker Street Underground Station serves multiple lines, including the Bakerloo, Jubilee, Metropolitan, Circle, and Hammersmith & City lines. This makes it one of the best-connected locations in London.
  • Diverse office spaces – The area offers a mix of modern office buildings and converted period properties, catering to businesses of all sizes. Whether you need a serviced office, a traditional lease or a flexible co-working space, Baker Street has options to suit.
  • Surrounding amenities – The street is lined with cafés, restaurants and shops, and is just a short walk from Regent’s Park, offering green space for lunch breaks.

Who thrives in Baker Street?

Baker Street is particularly attractive to professional services firms, legal practices and financial consultancies. However, it is also a great fit for tech companies and media businesses looking for a central yet slightly quieter alternative to Soho or the City.

For businesses seeking commercial space for lease in a location that blends history, convenience and prestige, Baker Street is a prime choice.

What’s on offer in Baker Street?

10 Portman Square - 5,000 square feet of corner office space with a 24-hour manned reception, views over the square, a passenger lift, seven showers and 124 bicycle spaces. Located on the north eastern corner of the square, the property has a main entrance on the southern tip of Baker Street, plus an additional cycle entrance to the rear on Baker's Mews.

Great Portland Street – The creative and media district

Great Portland Street has long been a magnet for creative industries, media companies and fashion brands. Located between Marylebone and Fitzrovia, it offers a dynamic business environment that attracts forward-thinking companies looking for a central yet slightly less corporate setting.

Why choose Great Portland Street for your business?

  • Creative and vibrant atmosphere – The area is popular with design agencies, publishing houses and digital media companies, making it an inspiring environment for businesses that thrive on innovation.
  • Varied office spaces – Great Portland Street offers a mix of warehouse-style offices, contemporary co-working spaces and high-spec commercial buildings and caters to companies of all sizes.
  • Excellent connectivity – Served by Great Portland Street Station (Hammersmith & City, Circle, and Metropolitan lines), as well as nearby Oxford Circus and Regent’s Park stations, the area offers excellent transport links.
  • Proximity to Oxford Street and Regent’s Park – Businesses benefit from access to world-class retail, restaurants and green spaces, making it an attractive location for employees and clients alike.

Who thrives in Great Portland Street?

This area is a great fit for the likes of creative agencies, fashion brands, architects and media companies. The eclectic mix of workspaces and stylish surroundings make it an ideal base for businesses that want to be in a central location, without the corporate feel of more traditional office districts.

For companies seeking commercial space for lease in an energetic and inspiring area, Great Portland Street provides the perfect blend of connectivity, character, and creativity.

What’s on offer in Great Portland Street?

33 Great Portland Street – one of the most notable buildings in the area, Great Portland Street was developed in 2015 as prime Grade A office accommodation. The available space is on the third floor, offering 2,400 square feet fitted out to a high standard with contemporary features. Location wise, the building is just a few minutes’ walking distance from a wide variety of shops, cafés and restaurants around Market Place, Regent Street and Oxford Street.

Cavendish Square – Prestige and professional services

Cavendish Square is one of Marylebone’s most prestigious addresses, offering businesses an elegant and well-connected location in the heart of London’s West End.

Known for its grand Georgian buildings and professional environment, it is a prime destination for companies seeking a refined setting with easy access to the city’s key business districts.

Why choose Cavendish Square for your business?

  • Prestigious location – With its historic architecture and exclusive address, Cavendish Square is an excellent choice for businesses that want to project an image of sophistication and credibility.
  • Popular with professional services – The area is home to legal firms, financial consultancies and private healthcare providers, thanks to its proximity to Harley Street and Oxford Circus.
  • Transport and accessibility – Oxford Circus Underground Station (Bakerloo, Central, and Victoria lines) is just a short walk away, ensuring seamless connectivity across London.
  • Green Space in the heart of the city – Cavendish Square’s central garden offers a rare pocket of tranquillity for professionals looking to step away from the hustle and bustle during the working day.

Who thrives in Cavendish Square?

Cavendish Square is particularly suited to businesses in finance, law, healthcare, and corporate consultancy, as well as companies that require a highly presentable office environment for client-facing operations.

For those looking for commercial space for lease that combines prestige, convenience, and a professional atmosphere, Cavendish Square stands out as a premier choice.

What’s on offer in Cavendish Square?

17 Cavendish Square is a Grade II listed Georgian building offering fully furnished serviced offices and a modern reception. Meeting rooms with video conferencing facilities are included, as are reception, call answering, mail handling and business support services. The building also offers modern, fully fitted kitchens, a shower room and professional cleaning throughout the day.

Wigmore Street and James Street – Retail and Office Blends

Wigmore Street and James Street offer a unique combination of office and retail spaces, making them ideal for businesses that benefit from high footfall and a lively commercial environment.

Located just minutes from Oxford Street and Bond Street, these areas provide the perfect setting for companies looking for a balance between corporate presence and customer engagement.

Why Choose Wigmore Street or James Street for your business?

  • Proximity to prime shopping areas – With Oxford Street and Bond Street just a short walk away, these locations benefit from exceptional visibility and foot traffic.
  • Retail and office synergy – There is a good mix of office and customer-facing spaces in these areas, making them ideal for brands that need showroom or client interaction areas alongside corporate offices.
  • Excellent transport links – Bond Street Underground Station (Jubilee, Central and Elizabeth lines) provides fast connections across London, including a direct link to Heathrow Airport.
  • Vibrant atmosphere – Surrounded by restaurants, cafés and boutique stores, the area offer a dynamic work environment that blends business with leisure.

Who thrives in Wigmore Street and James Street?

These locations are particularly attractive to luxury brands, creative agencies, fashion houses, and high-end service providers that benefit from a strong retail and business presence.

For companies looking for commercial space for lease in a prime London location with a mix of office and customer-facing opportunities, Wigmore Street and James Street offer the perfect solution.

What’s on offer in Wigmore Street and James Street?

1 James Street offers a total of 18,590 square feet of contemporary, sustainable office space split into two areas and including a roof terrace and pavilion.

Also at 1 James Street there is another option to let an economical part fourth floor office covering 3,368 square feet. The suite is being refurbished to provide Grade A accommodation, benefiting from a terrace spanning its entire length.

Looking for commercial space for lease in Marylebone? Talk to Mellersh & Harding, the London commercial property specialists.

If you are seeking high quality commercial space for lease, Marylebone could prove the perfect location.

At Mellersh & Harding we have a vast portfolio of commercial property on offer. Why not get in touch today to discuss your individual requirements? You can reach our dedicated team on 020 7522 8500.

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